New Drug Should Benefit Majority of Cystic Fibrosis Patients

A triple-combination drug has been shown to be effective in improving lung function for the majority of patients with cystic fibrosis. The new therapy should provide therapeutic benefits for 90 percent of all patients with the genetic disease.

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Some People are Resilient to Alzheimer's
Some People are Resilient to Alzheimer's

Researchers believe that some people -- perhaps 30 to 50 percent of the population -- are resilient to the effects of Alzheimer's disease.

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The Quest for Quality in Clinical Trials
The Quest for Quality in Clinical Trials

The Association of Clinical Research Professionals is focused on workforce training and development to ensure clinical trials are well designed, executed, and reported to move the science forward.

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New Breathing Tube for Cardiac Arrest Could Save Thousands
New Breathing Tube for Cardiac Arrest Could Save Thousands

A study comparing two breathing tubes used by paramedics during out-of-hospital cardiac arrest shows that the King laryngeal tube was superior to the more commonly used endotracheal tube.

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Caffeine Consumption can aid in Pain Modulation
Caffeine Consumption can aid in Pain Modulation

According to a 2014 study, 85 percent of the U.S. population consumes at least one caffeinated beverage per day, with coffee as the leading source by far, for an average intake of 165 mg per day across all age groups.

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Improving Sleep Quality for Breast Cancer Survivors
Improving Sleep Quality for Breast Cancer Survivors

A study by researchers at the UAB School of Health Professions published in Medicine & Science in Sports & Exercise, the official journal of the American College of Sports Medicine, connects aerobic physical activity -- like walking -- to better sleep for post-primary treatment breast cancer survivors.

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Drug Slows Brain Damage in Multiple Sclerosis
Drug Slows Brain Damage in Multiple Sclerosis

Results from a clinical trial of more than 250 participants with progressive multiple sclerosis revealed that ibudilast was better than a placebo in slowing down brain shrinkage.

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Researcher Finds Risk of Later Death after Donor Blood, Marrow Transplant in Childhood
Researcher Finds Risk of Later Death after Donor Blood, Marrow Transplant in Childhood

While blood and marrow transplants can save the life of a pediatric cancer patient, research out of the UAB found that those patients may be at an increased risk of premature death years or even decades after the procedure as compared with the general population.

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Big-Data Helps Define the Burden of Sarcoidosis
Big-Data Helps Define the Burden of Sarcoidosis

Physician-scientists from UAB using big-data recently summarized in the Journal of the American Heart Association the prevalence of cardiovascular manifestations, rates of defibrillator placement (ICD) and predictors of in-hospital mortality in sarcoidosis -- a disorder that affects multiple organs.

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Drinking Sugary Drinks may be Associated with Greater Risk of Death
Drinking Sugary Drinks may be Associated with Greater Risk of Death

Adults who are 45 years old or older and who consume large amounts of sugary beverages, including soft drinks, fruit drinks and fruit juices, may have a higher risk of dying from heart disease or other causes, compared to those who drink fewer sugary drinks, according to new research.

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Improving Sleep Quality for Breast Cancer Survivors
Improving Sleep Quality for Breast Cancer Survivors

A study by researchers at the UAB School of Health Professions published in Medicine & Science in Sports & Exercise, the official journal of the American College of Sports Medicine, connects aerobic physical activity -- like walking -- to better sleep for post-primary treatment breast cancer survivors.

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UAB Study Shows Link Between Microbiome in the Gut and Parkinson's
UAB Study Shows Link Between Microbiome in the Gut and Parkinson's

There is growing evidence showing a connection between Parkinson's disease and the composition of the microbiome of the gut.

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Brookwood Baptist Cardiovascular Research Takes a Leading Role in Two International Trials
Brookwood Baptist Cardiovascular Research Takes a Leading Role in Two International Trials

Can stem cells mend a broken heart? Which approach to managing carotid stenosis is the best option to help which patients avoid a stroke?

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HudsonAlpha Rearchers Identify Genetic Variants That Cause Intellectual Delay

Researchers at the HudsonAlpha Institute for Biotechnology, along with an international team of collaborators from six countries, have identified a new genetic disorder that causes intellectual and developmental delay in children.

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UAB Involved in Study Identifying Genomic Features of Cervical Cancer

Investigators with The Cancer Genome Atlas Research Network, including a researcher from the UAB, have identified novel genomic characteristics of cervical cancer that will aid in the subclassification of the disease and may help target therapies that are most appropriate for each individual patient.

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New England Journal of Medicine Lauds UAB Study

A study on the efficacy of surgery to remove the thymus in myasthenia gravis (MG) patients, led by researchers at UAB, has been named one of the top neurology stories of 2016 by the New England Journal of Medicine Journal Watch.

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Administering Additional Antibiotic Prior to C-section Reduces Infection Rates by 50 Percent
Administering Additional Antibiotic Prior to C-section Reduces Infection Rates by 50 Percent

Physicians at UAB and colleagues have discovered that administering the antibiotic azithromycin alongside the standard recommended antibiotic regimen, cefazolin, reduces infection rates by 50 percent for women who have a non-elective cesarean delivery.

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Researchers Develop a Test for Early Stage Ovarian Cancer

With funding providing by the Laura Crandall Brown Foundation and the Ovarian Cancer Institute, researchers at Georgia Tech have developed a method to detect ovarian cancer that is highly accurate in patients with Stage 1 disease.

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UAB Team Identify Protein that plays Key Role in Brain Cancer Stem Cell Growth
UAB Team Identify Protein that plays Key Role in Brain Cancer Stem Cell Growth

A team of physicians and scientists at UAB discovered that a kinase protein, mixed lineage kinase 4, also known as MLK4, plays a crucial role in survival of patient-derived brain cancer stem cells in pre-clinical animal models. The findings suggest that MLK4 could potentially be a useful target for cancer treatment.

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UAB Heads Two New National Rehab Research Centers
UAB Heads Two New National Rehab Research Centers

"The challenge of this is not only building the center, but attracting users across the national community and for them to become aware of what we have to offer," says Marcas Bamman, PhD, director of the new REACT Center and MR3 Network Coordinating Center at UAB.

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